The following is courtesy of J.D.S.
Several important therapeutic techniques were pioneered at St. Elizabeths, and it served as a model for later institutions. Carl Jung, for example, studied African-American patients at St. Elizabeths to examine the concept of race in mental health. Walter Freeman, onetime laboratory director, was inspired by St. Elizabeths to pioneer the transorbital lobotomy. During American involvement in World War II, the Office of Strategic Services (OSS, predecessor to the CIA) used facilities and staff at St. Elizabeths hospital to test "truth serums". OSS unsuccessfully tested a mescaline and scopolamine cocktail as a truth drug on two volunteers at St. Elizabeths Hospital. Separate tests of THC as a truth serum were equally unsuccessful.